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Caffeine

Caffeine is a stimulant that keeps you alert by blocking adenosine, the brain's sleepiness signal. Healthy adults can have up to 400 mg a day, about four cups of brewed coffee.

400 mga day at most for adults

200 mg in one go, or a day in pregnancy

Under 18 · 3 mg per kg of body weight a day

  • Most per 100 g 47mg Dark chocolate
  • Most per portion 97mg 1 cup coffee
  • Half-life ~4 h on average, from about 2 to 8 h
  • Main sources Coffee and tea then cola, energy drinks and chocolate

Limits: EFSA scientific opinion on the safety of caffeine (2015); the FDA uses the same 400 mg figure. Food figures per 100 g from USDA FoodData Central and CIQUAL.

Per 100 g vs. a Usual Portion

Why the food that ranks first per 100 g can give less in a real serving.

Amount per 100 g and in a usual portion
Food Usual portion Per 100 g Per portion
Coffee 1 cup (240 g) 40.6mg 97mg
Cola 1 can (354 g) 9.4mg 33mg
Dark chocolate 2 squares (20 g) 47mg 9.4mg
Milk chocolate 2 squares (20 g) 20mg 4mg
Ice cream 1 cup (135 g) 1mg 1.4mg

Dark chocolate has more caffeine than coffee per 100 g, but a cup of coffee weighs about 12 times as much as two squares of chocolate, so the cup gives about ten times the caffeine.

How Caffeine Works

Caffeine (1,3,7-trimethylxanthine) is a plant compound found in coffee beans, tea leaves, cacao, kola nuts, guarana and yerba mate. The body has no need for it. It is on this page because it is the most widely used stimulant in the world and it shows up in food labels, drinks and supplements.

While you are awake, a molecule called adenosine builds up in the brain and makes you feel sleepy. Caffeine has a similar shape and sits on adenosine's receptors without switching them on, so the sleepiness signal is muted. It does not add energy; it hides the tiredness that is already there.

How Long Caffeine Stays in Your Body

The gut absorbs nearly all the caffeine in a drink, and blood levels peak within about 30 to 60 minutes. The liver then clears it, mainly through one enzyme, CYP1A2. In healthy adults half of a dose is gone after about 4 hours on average, with a range of roughly 2 to 8 hours between people.

Smoking speeds clearance up. Pregnancy slows it a lot, especially in the last months, and so do birth control pills and medicines that block CYP1A2, such as the antibiotic ciprofloxacin and the antidepressant fluvoxamine. On those, the same coffee lasts much longer.

How Much Caffeine Is Left at Bedtime

Drink 1 cup of brewed coffee from the Caltide library at 3 pm and you take in 97 mg. With a 4 hour half-life, this is roughly what is left as the evening goes on.

Caffeine left from one cup at 3 pm, at an average 4 hour half-life. Your own clock may run faster or slower.
Time Left in the body
3 pm ~97mg
7 pm ~48mg
11 pm ~24mg
3 am ~12mg

EFSA notes that 100 mg close to bedtime can delay sleep and shorten it in some adults. One cup at 3 pm is down to about half by 7 pm and a quarter by 11 pm. A second cup later in the afternoon adds to what is left, and slow clearance, as in pregnancy, keeps far more of it in the blood at bedtime.

How Fast 400 mg of Caffeine Adds Up

Most foods have no caffeine at all, so a day's total comes from a handful of drinks and treats. This sample day uses foods from the Caltide library, in usual portions.

One ordinary day of food
Meal Food Amount Caffeine
Breakfast Coffee 240g 97mg
Breakfast Oats 40g 0mg
Lunch Pizza 119g 0mg
Lunch Cola 354g 33mg
Snack Dark chocolate 20g 9.4mg
Snack Coffee 240g 97mg
Treat Ice cream 135g 1.4mg
Total 238mg

That is 238 mg, 60% of the 400 mg adult limit, before any tea, energy drink or pre-workout scoop.

Caffeine With Food and Other Nutrients

Coffee and tea drunk with a meal lower how much plant iron the body absorbs. The polyphenols in the drink do this, not the caffeine itself. People low in iron can drink them between meals instead. Tea also brings theanine, an amino acid studied for how it may shape caffeine's effect on alertness.

Common Caffeine Mistakes

Counting cups, not milligrams. A large takeaway coffee can be twice the size of a 240 ml cup, or more. Count the size of the cup, not the number of them.

Forgetting the hidden sources. Cola, energy drinks, iced tea, chocolate, some pain relievers and pre-workout powders all carry caffeine. Guarana and green tea extract on a label contain caffeine too.

Treating the jitters as normal. A racing heart, shaky hands, anxiety, an upset stomach or poor sleep are the usual signs of too much. Regular drinkers build tolerance, and stopping suddenly can bring a headache and tiredness for a few days.

How Much Caffeine Is Safe

Caffeine has no daily need, only limits. These are the amounts EFSA found raise no safety concern.

Caffeine from all sources combined (EFSA, 2015)
Who Up to
Healthy adults 400 mg a day
A single dose, adults 200 mg at once
Pregnancy 200 mg a day
Breastfeeding 400 mg a day, 200 mg at once
Children and teenagers 3 mg per kg of body weight a day
Close to bedtime 100 mg can affect sleep

Caffeine in Supplements

Supplements are a common second source of caffeine, and the easiest one to overdo, because the dose is concentrated.

Names for Caffeine on Supplement Labels

  • Caffeine anhydrousplain caffeine with the water removed, the form in most pills and pre-workout powders
  • Guarana, green tea extract, yerba mate, kola nutplant extracts that contain caffeine; the label does not always say how much
  • Some pain relieversheadache tablets that combine caffeine with a painkiller list it among the active ingredients

Before You Take a Caffeine Product

Add its milligrams to your coffee, not instead of it. One 200 mg pill on top of two large coffees already passes 400 mg. Avoid pure caffeine powder and liquid concentrates: a very small amount holds a very large dose, and kitchen spoons cannot measure it safely.

Ask a doctor or pharmacist before combining a supplement with a medicine.

Tracking Caffeine in Caltide

  • Counted against your limitCaltide adds up the caffeine in every food and drink you log, shows the day's total in the Nutrition tab, and flags it once you pass the limit for your age: 400 mg for adults, 3 mg per kg of body weight under 18.
  • Pills and powders count tooAdd your caffeine pill or pre-workout once with its caffeine as an ingredient. Each day you check it off, it counts toward your total.

Caffeine Sources and References

The figures and claims on this page are checked against these sources. Food amounts come from USDA FoodData Central.

  1. EFSA: Scientific Opinion on the safety of caffeine (2015)
  2. US FDA: Spilling the Beans: How Much Caffeine is Too Much?
  3. USDA FoodData Central

Questions About Caffeine

For healthy adults, more than 400 mg a day. EFSA found no safety concerns up to 400 mg a day and up to 200 mg in one go. In pregnancy the figure is 200 mg a day; while breastfeeding, EFSA found up to 400 mg a day raises no concern for the baby.

Per 100 g, dark chocolate leads the Caltide food library with 47 mg, then Coffee (40.6 mg) and Milk chocolate (20 mg). Per portion, coffee has by far the most, because a cup weighs about 240 g and two squares of chocolate about 20 g.

Brewed coffee in the Caltide library has 40.6 mg per 100 g, so a 240 ml cup holds roughly 100 mg. The real figure depends on the beans, the grind and how strong you brew it.

EFSA puts its half-life at about 4 hours in healthy adults, with a range of roughly 2 to 8 hours, so half of a cup is still in your blood 4 hours later. Smoking shortens it, while pregnancy, birth control pills and some medicines make it longer.

Yes, a little. Decaffeination removes most of the caffeine, not all of it, so several cups of decaf add up to a small amount.

Not at usual intakes. Caffeine has a mild diuretic effect, but in people who drink coffee or tea regularly the water in the drink makes up for it, so these drinks count toward your daily fluids.

EFSA uses 3 mg per kilogram of body weight a day for children and teenagers. For a 50 kg teenager that is 150 mg, about one and a half cups of brewed coffee.

The caffeine is the same molecule. Pills and pre-workout powders state an exact dose, often 100 to 200 mg, which makes them easy to stack on top of coffee without noticing. Pure caffeine powder is the risky one: a tiny scoop can hold a dangerous dose.

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